Apollo Pharmacy stops selling Ranbaxy drugs
Submitted by Manpreet Dhillon on Fri, 06/07/2013 - 17:17.
Branded drug retailer Apollo Pharmacy has temporarily stopped selling Ranbaxy medicines as a cautionary measure, according to a fresh Business Standard report.
Shobana Kamineni, executive director of Apollo Hospitals, told the publication that the company's medical committee recommended temporarily suspension of Ranbaxy medicines, saying the company could not take a chance with patients' safety.
Quoting Kamineni, the publication reported, "Our medical committee. recommended, as a cautionary measure, we should temporarily suspend sale of Ranbaxy medicines. So, we have immediately issued an advisory to our pharmacies."
The executive director also revealed that the company had asked Ranbaxy Labs to furnish some details, including re-certification of the existing stock of drugs and test reports for its other medicines.
Last month, Ranbaxy Labs pleaded guilty to felony charges in the United States related to manufacturing practices at two of its Indian facilities. The drug giant agreed to settle the charges by paying $500 million.
Apollo Pharmacy is India's biggest branded drug retail network, with more than 1,500 outlets across the country.
Ranbaxy shares slipped nearly 1 per cent to Rs 376 apiece on the National Stock Exchange (NSE) in early trade on Friday. Since the company pleaded guilty, the stock has shed 15 per cent.
Dr Reddy’s shares jump on U.S. launch of Decitabine for injection
Submitted by Piyush Diwan on Sat, 07/13/2013 - 20:13.
Stock in Dr Reddy's Laboratories gained more than 1 per cent on Friday; a day after the company announced the launch of a therapeutic equivalent generic version of Dacogen called Decitabine for injection in the U. S. market.
Dr Reddy's Labs said it launched Decitabine for injection as 50mg single dose vial, after obtaining the approval of the U. S. Food & Drug Administration (USFDA).
During the twelve months ended July 2013, the Dacogen brand recorded sales of around $260 Million MAT in the U. S.
The foreign institutional investors (FIIs) held 32.69 per cent stake in Dr Reddy's Labs in June 2013 quarter, up by more than 3 percentage points from the previous quarter.
Shares of the drug maker jumped to a record high of Rs 2,327.10 apiece in the afternoon trade on Bombay Stock Exchange (BSE), up 1.57 per cent from its previous close. On the National Stock Exchange (NSE), the stock opened at Rs 2,301 and jumped to Rs 2,317 apiece. A combined more than 158,729 shares of Dr Reddy's Labs changed hands on both BSE and NSE.
Karvy Stock Broking maintained its `Buy' rating on Dr. Reddy's Labs' stock at a target price of Rs 2,502 along with potential upside of 9 per cent.
UK drug regulator bans 16 medicines made in India
Submitted by Sameer Kapoor on Fri, 07/12/2013 - 19:02.
UK drug regulator Medicines & Healthcare Products Regulatory Agency (MHRA) has banned the sale of 16 medicines manufactured by Wockhardt Ltd's Waluj factory in India.
The MHRA ordered the ban after it identified several manufacturing deficiencies at the drug maker's Waluj, Maharashtra-based manufacturing plant during a routine inspection conducted in March. The list of identified manufacturing deficiencies included cross-contamination and data falsification.
While directing pharmacies, dispensing clinics and wholesalers to immediately stop selling the drugs, the regulator also said that it found no evidence of any defect in the medicines and therefore patients who already have purchased the medicines didn't need to return them.
Ordering the ban, the regulator said, "Though the medicines that are affected have not been manufactured to Good Manufacturing Practice (GMP) standards, there is no evidence of a patient safety risk from medicines that have been sold in the UK."
It underlined that it was not a patient-level recall, and that the step was taken in the interests of public health as poor manufacturing standards couldn't be allowed to continue.
Wockhardt's exports out of the Waluj facility accounts for the company's less than 5 per cent of total sales in the UK, but the one-off impact of the recall would be as high as 1.5 million pounds.
Last Updated: Wednesday, August 14, 2013, 15:01
Washington: A
new discovery by researchers has helped to take the fight against
antibiotic-resistant superbugs a step forward.
A
multi-disciplinary research team at the University of Nottingham`s
Centre for Biomolecular Sciences has uncovered a new way of
inhibiting the toxicity and virulence of the notorious superbug,
Pseudomonas aeruginosa.
These bacteria
produce an armoury of virulence factors and are resistant to many
conventional antibiotics. It is almost impossible to eradicate P.
aeruginosa from the lungs of people with cystic fibrosis and is
therefore a leading cause of death among sufferers. The bug also
causes a wide range of infections particularly among hospital
patients.
The new
discovery concerns the bacterial cells` ability to `talk` to each
other by producing and sensing small chemical signal molecules.
This is called `quorum sensing` (QS) and enables a population of
individual bacteria to act socially rather than as
individuals.
QS
allows a population of bacteria to assess their numerical strength
and make a decision only when the population is
`quorate`.
The
mechanism through which QS signals work is by activating gene
expression upon interaction of a QS signal molecule with a receptor
protein. In many disease-causing bacteria, QS controls genes which
are essential for infection.
These genes code
for virulence factors such as toxins which cause damage to host
tissues and the immune system. Interfering with the QS signalling
process blocks bacterial virulence and renders bacteria unable to
cause infection.
Consequently QS
systems are molecular targets for the development of new
anti-infective drugs which do not kill bacteria but instead block
their ability to cause disease.
In a
study, the team described how they solved the 3D structure of a
receptor protein called PqsR used by P. aeruginosa to sense alkyl
quinolone QS signal molecules so that they could visualize the
shape of the QS signal molecule-binding site within the PqsR
protein.
Professor of
Molecular Microbiology, Paul Williams, said that they are able to
synthesize and screen a library of chemical compounds which could
fit within the PqsR binding site and block receptor activation by
the QS signal molecules.
Williams added
that the active compounds were screened for their ability to
inhibit QS and through a process of chemical refinement some novel
potent QS inhibitors were discovered which were tested biologically
on P.aeruginosa and shown to block virulence gene
expression.
Diabetes and BP are enemies of Kidney: Dr Vyanketesh Joshi.
IBNLive.com | Updated Jul 03, 2013 at 04:32pm IST
Web-based & uniquely accurate! Sign Up for a Free user account.www.vithoulkascompass.com |
According to doctors, 10 per cent of Indian people suffers from chronic kidney disease. More than 90 percent of the 230,000 people who develop chronic kidney failure each year in India die within months because of lack of treatment. Is there any alternative to allopathic treatment, dialysis and kidney transplant? Dr Vyanketesh Joshi, director of SDF Holistic Healthcare, joined IBNLive readers for an interaction on treating Kidney disorder through Ayurveda.
Q. Dear Dr. Joshi, My daughter is suffering from nephrotic syndrome since she was at the age of 3. She is now 8. She developed steroid resistance and hence was on a no. of drugs and now for more than 1 year is on dicaris. Is there any treatment available in Ayurveda. or it is on same principle of managing the disease until it gets corrected on its own. Asked by: Ashish Chadha
A. Nephrotic syndrome human disorder disease. We have very good treatment to boost the immune system. In our treatment we use only herbal medicine which is safe for kidney. We have treated many children those are suffering in nephrotic syndrome. For more details - SDF Holistic 37/4, Gorain Sangli CHS opp.Hotel Status, Gorai-2, Borivali (West), Mumbai-400092. Tel no.: 2967 3311 / 2967 2288 / 2967 3399 Helpline: 96197 77222 website: http://www.sdfholistic.com Email: contact@sdfholistic.com Follow us on http://www.facebook.com/sdfholistic.
Dr Vyanketesh Joshi, director of SDF Holistic Healthcare, on treating Kidney disorder through Ayurveda.
Q. I am 39 years old male and I have undergone kidney transplantation 2 years back and I am fine. My serum creatine level is 1.5 now. I did not go for a married life assuming my life is short. Can I go for a marriage now? if yes, what are the complications of the marriage life. Asked by: Sathish
A. You can go for marriage life we have good treatment to increase kidney life as well as marriage life. For more details............ SDF Holistic 37/4, Gorain Sangli CHS opp.Hotel Status, Gorai-2, Borivali (West), Mumbai-400092. Tel no.: 2967 3311 / 2967 2288 / 2967 3399 Helpline: 96197 77222 website: http://www.sdfholistic.com Email: contact@sdfholistic.com Follow us on http://www.facebook.com/sdfholistic.
Q. Which are the vegetarian items taxing on the kidneys? Asked by: sundar1950in
A. There are vegetarians items which should be low in alkaline levels are very essential for proper functioning of kidneys. Use cereals and proteins and avoid processed and dairy products which contains high level of alkalinity.
Q. How safe is it? I heard stories about people getting poisoned by this kind of medication. Asked by: Gauri
A. It is misconception. These medicines are made by only herbs so it is safe like food supplement. Metals & chemicals are not good.
Q. Sir, what would be the symptoms of a Kidney disorder? Asked by: Suresh Sitaram
A. Kidney disorders are many from kidney stones which can lead to blood in your urine, CKD (Chronic kidney failure) symptoms can be swelling on the body, breathlessness, urine output becomes low and in advanced stages patient can go into dialysis ( to remove the toxins accumulated in the kidneys).Symptoms like fatigue, nausea, vomiting, changes in urination.
Q. Sir, my mother was suffering from CKD V and we were advised to go for Ayurveda alongside Allopathy. When we shared this with our Nephrologist, he was not quite happy with our decision. Is it wrong to have both Ayruvedic medicines along with Allopathic, also why do doctors discourage their patients to stop Ayurvedic medicines? Asked by: Prashant
A. Nephrologists are not aware about the benefits of Ayurvedic medicines. They are under impression that each & every medicines have metals which is wrong. These Medicines are prepared by herbs it is very safe. You can go for simultaneous treatment.
Q. Is there a possibility to improve the condition of a patient who is already under Dialysis, under the Ayurveda? Asked by: sundar1950in
A. Yes we can improve the condition of the patient with our Herbal medicines and Panchakarma Therapies. With this treatment kidney's function is maintained and helps in easy filtering of water and wastes from the body. When taken regularly for prolonged periods, may help to reduce the frequency of dialysis and improve kidney function.
Q. What are the areas in which kidney can become a problem for a sugar patient? Asked by: sundar1950in
A. Diabetes and blood pressure are the most common enemies of the kidney failure. Those are under treatment of diabetes & BP should avoid pain killers.
Q. Is there an effective treatment for Kidney failure? What is the alternative to dialysis and transplantation? What is the track record in this regard? Asked by: Raja Chandra
A. There is effective treatment available in SDF Holistic Centres in Mumbai & Thane. Many patients have benefited with our treatment.
Q. My grandmother is 82 years of age and has started developing Kidney problems. She is currently under extensive medication and doctors say her kidney is now only 80 percent functional. Her condition in deteriorating with every passing day. Can Ayurveda cure kidney problems for elderly? Asked by: Rajneesh
A. Considering your grandma age our treatment is very beneficial, which is very safe. Kindly refer our website.
Q. My Father has creatinie level as 4 and he's taking medication given by nephrologist, is anything else u can recommend which will help. We are in Bangalore. Also can kidney disorder can cause continuous fever? Asked by: Rakesh
A. Your father's case is very good to avoid the dialysis. We have very good herbal medicines which help to reduce the Cerum Creatinine level within short period. Kindly refer our website. www.sdfholistic.com
Q. Is banana stem good to keep Kidney function efficient? Asked by: sundar1950in
A. Banana is good for kidney and health. Provided you should check renal function test.
Q. Is it true that too much of Tomatoes can cause kidney problems. Asked by: sundar1950in
A. Everything is good in balance, excess tomatoes are bad because it contains seeds.
Q. When there is a spare kidney provided, will it not automatically take care of the problem in the functional kidney? Asked by: sundar1950in
A. Sorry I didn't get you question. For more details............ SDF Holistic 37/4, Gorain Sangli CHS opp. Hotel Status, Gorai-2, Borivali (West), Mumbai-400092. Tel no.: 2967 3311 / 2967 2288 / 2967 3399 Helpline: 96197 77222 website: http://www.sdfholistic.com Email: contact@sdfholistic.com Follow us on http://www.facebook.com/sdfholistic.
Prime Minister
Manmohan Singh said on Thursday the National Rural Health Mission
(NRHM) had started showing good results and had helped bring down
both maternal and infant mortality rates. ‘We had launched the
National Rural Health Mission in 2005. (It) has started showing
good results. Both maternal and infant mortalityrates have come down sharply,’ he said
in his Independence Day speech. He said: ‘A much larger proportion
of children are now born in hospitals. There has also been a large
increase in the proportion of children being
inoculated.’
The NRHM is the government’s flagship programme for improving healthcare delivery across rural India. ‘We have implemented the health mission in urban areas also. This will result in both expansion and improvement of health services in such areas,’ the prime minister said. He said the Rashtriya Swasthya Bima Yojana (National Health Insurance Scheme), which provides free in-patient treatment in hospitals to ‘our poor brothers and sisters’, now covers about 3.5 crore families.
What is the NRHM?
The National Rural Health Mission (NRHM) is an ambitious plan to improve health delivery in rural India where access to even the most basic services is very low. The scheme has been called by some economists ‘the most ambitious rural health initiative ever’ and takes a more practical approach by training local residents in primary healthcare.
Last year’s (2012-13) budget increased allocation to two of the biggest projects to alleviate the healthcare woes of the poor – the National Rural Health Mission (NRHM) and the Rashtriya Swasthya Bima Yojana (RSBY) which literally means the National Health Insurance Scheme.
The NRHM was a rural health initiative started in 2005, to alleviate the healthcare woes of rural India. The way it works is the government picked out 264 backwards districts to improve healthcare services which they would seek to improve the healthcare facilities in these places with a more pragmatic approach. This involved training locals as Accredited Social Health Activists (ASHA) and various indicators suggest that it has worked to a certain extent. Last year, the NRHM was allocated Rs 20,822 crore (increased from Rs 18,115 crore in 2011). Like the NRHM, the RSBY is mainly for the poor who can’t afford health insurance. It is a smart-card based insurance scheme for every Below-Poverty Line (BPL) family which allows them to get inpatient treatment up to Rs 30,000 per year. The scheme will cover the main bread earner, their spouse and three dependents. In 2012, the RSBY was allocated Rs 1097.6 crore.
PM Manmohan Singh lauds polio-free India!
IANS August 15, 2013 at 1:11 pm
India has
been able to eradicate polio which used to cause disability to
lakhs of people, Prime Minister Manmohan Singh said on
Thursday.
‘No case of polio has been detected in the country in the last two years. We have been able to eradicate a disease which used to cause disability to lakhs of people,’ Manmohan Singh said in his Independence Day address from the ramparts of the Red Fort.
What is polio?
Polio or poliomyelitis is a communicable viral disease which affects the nerves and can lead to partial or permanent paralysis. It is transmitted through stool or saliva. The global effort to eradicate polio has been very successful and from 350,000 cases in 1988 only 40 cases were reported worldwide in 2012. There is no cure for the diseases though vaccination can prevent the disease for life. India has done remarkably in eradicating polio and from 2011 no new cases were reported.
Scientists find a possible cure for childhood cancers
India.com Health August 17, 2013 at 9:07 am
Now scientists
have found a way to target the structure of cancer cells, making
the treatment of cancer that much more possible.
Researchers at the University of New South Wales (UNSW) demonstrated that the therapy is effective in two types of cancers in the animal model – namely neorublastoma (cancer that affects children) and melanoma (skin cancer). Scientists say that the drug causes the collapse of the structure of the cancer cells. Since this process happens relatively quickly and is effective against every type of cancer cells, it has given scientists hope for more new age treatments for ailments like cancers in children.
This new line of treatment could lead to an entirely new type of chemotherapy, which could have more positive outcomes for hard-to-treat cancers and have fewer long-term side effects for survivors.
Lead scientist Dr Justine Stehn from the Oncology Research Unit, in the School of Medical Sciences, says that targeting the architecture of cancer cells has long been the aim of almost all studies, but because these building blocks also make up the heart and muscles, attacking those cells was impossible. Soon they found that there was another building block that was unique to cancer cells – tropomyosin. This compound in the cancer cell structure was sufficiently different from those in the heart and muscle, and could be safely targeted.
Over 55 and love coffee? Here is some advice for you
IANS August 17, 2013 at 10:23 am
If you have been fond of drinking coffee many times in a day, beware! A new study has found a link between heavy coffee consumption and increased death risk for people aged below 55.
The US study, published in the journal Mayo Clinic Proceedings, found a statistically significant 21 percent increased mortality among those who drink more than 28 cups of coffee a week or four cups of coffee a day, Xinhua reported. Based on age groups, the study found that the risk of death from all causes risen by more than 50 percent for men and women who were younger than 55. But no adverse effects were noticed in heavy coffee drinkers aged over 55.
In this study, researchers from the University of South Carolina, US examined the coffee consumption of more than 43,000 individuals aged between 20 and 87 years from 1971 to 2002. During the 17-year median follow-up period, more than 2,500 participants died. It was found that younger men had a trend towards higher mortality despite lower consumption. But this became significant at about 28 cups per week where there was a 56 percent increase in mortality from all causes.
Younger women who consumed more than 28 cups of coffee per week had double the risk of dying from all causes than those who did not drink coffee, the study said. ‘For those drinking high amounts, there should be some caution, as this dose was associated with at least a signal for increased total mortality in this large study, especially in those under 55 years of age,’ Xuemei Sui, the study’s co-author from the University of South Carolina in Columbia.
Central government to provide financial assistance for haemophilia patients
IANS August 15, 2013 at 1:11 pm
The central
government will provide financial assistance under the National
Rural Health Mission (NRHM) to state governments to help
haemophilia patients, the Rajya Sabha was
informed.
The Rashtriya Bal Swasthya Karyakram, launched by Congress President Sonia Gandhi Feb 6 under NRHM provides facilities for early detection and treatment of haemophilia, Health Minister Ghulam Nabi Azad said in a written reply on Tuesday.
He said state governments could submit proposals for treatment of haemophilia cases in their respective programme implementation plans for consideration of central assistance.
Azad said diagnosis and treatment facilities for haemophilia disease are also available in central government hospitals like Lady Hardinge Medical College, Sucheta Kriplani Hospital, Safdarjung Hospital and Ram Manohar Lohia Hospital (all in New Delhi) and Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry.
What is haemophilia?
Haemophilia, a congenital lifelong bleeding disorder that prevents the blood from clotting properly, leads to patients bleeding internally, mostly in the joints, muscles and vital organs like the brain. In many cases, the disease leads to permanent disability.
India has nearly over 100,000 haemophilia patients, most of whom face severe problems in treatment with only a few able to afford the high costs.
Jubilant’s molecule gets USFDA approval for drug trials
India.com Health August 11, 2013 at 11:52 am
The US Food
& Drug Administration (FDA) accepted the novel molecule of the
Bangalore-based Jubilant Biosys Ltd for clinical trials to treat
prostate cancer,
the pharma company said on Saturday. ‘The FDA acceptance of
our investigational new drug relates to the new molecule targetting
prostate cancer. Approval of our filing paves way for the next
stage of development and clinical trials later this year,’ Jubilant
drug discovery services president Subirkumar Basak said in a
statement.
As a subsidiary of the pharma major Jubilant Life Sciences, Biosys provides integrated drug discovery solutions to pharma firms worldwide. The drug trials will be conducted in collaboration with the US-based Endo Pharmaceuticals Ltd. ‘Being at the forefront of pharmaceutical, life sciences and healthcare innovation, we pursue our goal to enable affordable healthcare to patients worldwide,’ Basak said. The filing and progression of the molecule to the next development stage also validates Endo’s collaborative drug discovery approach to improve patient outcomes.
‘Our multi-target oncology collaboration with Jubilant, which began four years ago, is focused on developing therapies that address the unmet needs of cancer patients worldwide,’ Endo’s discovery & early development vice-president Sandeep Gupta said in the statement.
Breastfeeding may reduce Alzheimer’s risk among women
IANS August 6, 2013 at 4:02 pm
A British study has suggested breastfeeding mothers run a lower risk of developing Alzheimer’s, with longer periods of breastfeeding further reducing the risk.
The study paper, published in the Journal of Alzheimer’s Disease, has suggested that the link may be to do with certain biological effects of breastfeeding. For instance, breastfeeding restores insulin tolerance which is significantly reduced during pregnancy, and Alzheimer’s is characterised by insulin resistance in the brain, Xinhua reported.
On the basis of data gathered from a group of 81 British women, researchers observed a highly significant and consistent correlation between breastfeeding and Alzheimer’s risk. They argued that this was so strong that any potential sampling error was unlikely.
‘Alzheimer’s is the world’s most common cognitive disorder and affects 35.6 million people,’ said the study’s lead author Molly Fox of the University of Cambridge.
Delhi hospital launches hereditary cancer test
IANS August 5, 2013 at 8:35 pm
With over one million people diagnosed with cancer every year in India, a hospital here has launched a hereditary cancer genetic testing service, a doctor said on Monday.
Sir Ganga Ram Hospital said the service will provide a new frontier in the fight against cancer with a focus on prevention.
The service will be run by trained genetic counselling experts, medical, surgical, paediatric oncologists and cyto-pathologists.
‘The experts will inquire about the history of cancer in the family members, identify the presence of other risk factors and provide an estimate of risk of an individual to develop cancer,’ said I.C. Verma , director, department of genetics, Ganga Ram Hospital.
Verma says risk management and preventive cancer counselling can help families to cope with increased risk for different cancers.
‘Those testing positive in the gene test are counselled regarding their risk for developing cancer. Those who are already affected with cancer are made to understand how genetic mutation can affect their future treatment,’ he said.
The cost varies for genetic testing of different cancers.
About 10 percent of cancers in adults and about 20 percent in children are hereditary.
The importance of genetic testing was highlighted by Hollywood actress Angelina Jolie, who tested positive for a mutation in the breast cancer gene, and opted for breast removal to prevent development of breast cancer in future.